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b) Toxicology |
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Oral:
None of the organisms exposed to AGROSTEMIN
for a period of 30 days has shown signs of poisoning or death. Samples taken of the organisms have not shown any damage of internal organs or tissues. Dermatological: None of the exposed organisms have shown signs of poisoning, death,
pathological alterations of the skin or the subcutaneous tissues. Inhalatory: Tests in inhalation rooms have been performed, with exposures of 0.58mg/l for a observation period of
30 days. None of the exposed organisms has shown signs of intoxication. The samples taken of lungs and other internal organs have not shown any damage or pathological alteration. Irritation
of skin and mucous membranes: None of the exposed organisms by a rate of 1.384mg/kg of body mass have shown edema or signs of irritation. No alteration of ocular membranes have been observed.
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From the points of view of pathology and clinic analysis, none of the organisms that have been given
AGROSTEMIN with its food, in doses of 1, 100 and 1000ppm have shown any alteration ore signs of intoxication of inner organs or tissues. |
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Tests performed on Salmonella Typhimurium
cultivation in concentrations of 0.1 to 1000ng/sample, with and without the presence of activator systems, have shown some signs of revertible genetic alteration. |
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Embryonic Toxicity and Teratology |
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Female organisms in state of pregnancy received AGROSTEMIN
doses of 0.1, 1, 10 and 100 mg/kg of body mass. In none of the breeds have been found malformations, therefore no secondary effects are considered to exist. |
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Effects on the Nervous System |
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Organisms have been exposed in several manners to doses of 25, 50, 100, 150, and 250 mg/kg of body mass. No
effects on the central nervous system have been observed. |
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Effects on Sensible Organisms |
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During the tests performed, there have been no signs which permit to deduce any kind of effect on sensible
organisms caused by any of the basic components of the product. |
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Toxical Information about the blends |
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The product and its components are of organic nature, therefore they do not represent any risk by being
mixed with other substances. |
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